Treatment

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Treatment and care of children with cancer is usually provided by a team of health professionals called a multidisciplinary team. Members of this team are specialists in children’s cancers – they understand the differences between children’s cancer and adult cancer, and each team member brings different skills in managing care to meet the needs of both you and your child.

The team will be led by a childhood cancer specialist (paediatric oncologist). Other members of the team depend on the age of your child and their type of disease, and may change over time as your child’s needs change. A list of team members who might make up the multidisciplinary team can be found in The treatment team.

Treatment for germ cell tumours depends on the age of your child, the stage of the disease, the biological features of the cancer and other factors identified during diagnosis. Treatment will be tailored to your child’s particular situation, and may involve one or more of the following (see How is cancer treated for more detail).

Surgery

Your child may have surgery to remove all or part of the tissue containing the tumour. This can include removing one or both testicles, or one ovary and one fallopian tube.

Chemotherapy

Chemotherapy uses anti-cancer medicines to destroy cancer cells. It is often given as a combination of medicines to try to prevent the cancer cells from becoming resistant to just one or two medicines.

Chemotherapy medicines are given together in courses, often over a few days. Once the body has recovered from the side effects, the next course is given. Most children receive multiple courses of chemotherapy.

Chemotherapy may be used before surgery (to shrink the tumour and make it easier to remove) or after surgery (to destroy any remaining cancer cells).

Radiation therapy

Radiation therapy (also called radiotherapy) uses high-energy X-rays or other types of radiation to destroy cancer cells or stop them from growing. Children with germ cell tumours in the brain may have radiation therapy.

Radiation therapy is not commonly used to treat germ cell tumours in the brain in children under 3 years of age because it can have long-term side effects on developing brains. Young children usually have chemotherapy instead, and may have radiation therapy once they are old enough. If radiation therapy is included in your child’s treatment, special care will be taken to reduce the risks.

Stem cell transplant

Some children with germ cell tumours in the brain may be treated using a stem cell transplant (also known as a bone marrow transplant), in combination with high-dose chemotherapy.

Careful observation

For a few carefully selected patients, specific treatment may not be needed. If your child has a tumour that is not growing or spreading, they might be monitored closely but not given any treatment until they develop symptoms, or until their symptoms change .

published: Sunday, 23 August, 2015